Genetic Disparities:
Genetic differences between the donor and recipient lead to the immune system rejecting the transplanted hair. The immune system’s strong response results in the rejection of the transplanted hair.
Environmental Impact:
The cellular environment in the donor area can affect the strength and quality of the harvested hair. Differences in vascularization and nourishment in the new environment make it difficult for the follicles to adapt, leading to their death and the failure of the procedure.

Can Hair Be Transplanted from an Identical Twin?
When hair is transplanted from an identical twin, there is a genetic match between the donor and recipient. This match can overcome some of the obstacles faced when transplanting hair from a genetically unrelated person.
Advantages of Hair Transplantation Between Identical Twins:
- DNA Match: Reduces the risk of the body rejecting the transplanted follicles.
- Immune System: The immune system regards the transplanted tissues from the identical twin as part of the body itself.
- Hair Characteristics: Characteristics such as color, texture, growth pattern, and vascularization will be very similar, ensuring natural and seamless results.
However, the recipient will still need to take immunosuppressive drugs after the procedure to ensure its success.